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Cancer
SCF-Mediated Degradation of p100 (NF-{kappa}B2): Mechanisms and Relevance in Multiple Myeloma
Luca Busino, Scott E. Millman, and Michele Pagano (4 December 2012)
Sci. Signal. 5 (253), pt14. [DOI: 10.1126/scisignal.2003408]
Ubiquitin-mediated degradation of an inhibitor of noncanonical NF-{kappa}B signaling promotes cell survival. Abstract »   Full Text »   PDF »   Slideshow »  
Molecular Biology
Protein Complexes and Target Genes Identification by in Vivo Biotinylation: The STAT5 Paradigm
Eleni Katsantoni (30 October 2012)
Sci. Signal. 5 (248), pt13. [DOI: 10.1126/scisignal.2003622]
Identification of a transcription factor’s interacting partners and target genes can reveal context-specific signaling and transcriptional outputs. Abstract »   Full Text »   PDF »   Slideshow »  

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