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- Cell Migration
Roles of GRK2 in Cell Signaling Beyond GPCR Desensitization: GRK2-HDAC6 Interaction Modulates Cell Spreading and Motility
- Petronila Penela, Vanesa Lafarga, Olga Tapia, Verónica Rivas, Laura Nogués, Elisa Lucas, Rocío Vila-Bedmar, Cristina Murga, and Federico Mayor Jr. (15 May 2012)
Sci. Signal. 5 (224), pt3. [DOI: 10.1126/scisignal.2003098]
GRK2 modulates tubulin acetylation dynamics in an HDAC6-dependent manner to affect epithelial cell spreading and motility.
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- Development
TGF-β Signaling in Endothelial-to-Mesenchymal Transition: The Role of Shear Stress and Primary Cilia
- Peter ten Dijke, Anastasia D. Egorova, Marie-José T. H. Goumans, Robert E. Poelmann, and Beerend P. Hierck (21 February 2012)
Sci. Signal. 5 (212), pt2. [DOI: 10.1126/scisignal.2002722]
The loss of primary cilia is a prerequisite for flow-induced endothelial-to-mesenchymal transition in heart development.
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