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COVER This week's issue introduces a new name, Science Signaling, and a new volume number to the Signal Transduction Knowledge Environment, and features an Editorial Guide on breakthroughs in cell signaling of 2007. [Image: Christopher Bickel, AAAS]

Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882