GABA Effects on Neurogenesis: An Arsenal of Regulation

Science Signaling  15 Apr 2008:
Vol. 1, Issue 15, pp. jc1
DOI: 10.1126/stke.115jc1

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The well-known inhibitory neurotransmitter GABA is excitatory to immature neurons during development as well as to neural progenitor cells during adult neurogenesis. Recent evidence indicates that GABA plays a role in regulating neurogenesis in various situations. This journal club paper aims to provide a skeleton description of GABA regulation of neurogenesis, describing some of the disparate mechanisms and scenarios in which it is involved.

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