GABA Effects on Neurogenesis: An Arsenal of Regulation

Sci. Signal., 15 April 2008
Vol. 1, Issue 15, p. jc1
DOI: 10.1126/stke.115jc1

GABA Effects on Neurogenesis: An Arsenal of Regulation

  1. Ti-Fei Yuan1,*
  1. 1The author is a graduate student in the Department of Anatomy, The University of Hong Kong, Li Kai Shing Faculty of Medicine, 21 Sassoon Road, Hong Kong.
  1. *Contact information. E-mail, yuantf{at}; telephone, 852-2249-1003


The well-known inhibitory neurotransmitter GABA is excitatory to immature neurons during development as well as to neural progenitor cells during adult neurogenesis. Recent evidence indicates that GABA plays a role in regulating neurogenesis in various situations. This journal club paper aims to provide a skeleton description of GABA regulation of neurogenesis, describing some of the disparate mechanisms and scenarios in which it is involved.


T.-F. Yuan, GABA Effects on Neurogenesis: An Arsenal of Regulation. Sci. Signal. 1, jc1 (2008).

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882