Fish use the lateral line to sense changes in pressure and water movements that may signal the arrival of food or predators. Nechiporuk and Raible now use genetics, cell transplantation, and live imaging to study lateral line development in zebrafish. In zebrafish, the lateral line develops from front to back, with a migrating zone of progenitor cells laying down repeated clusters of hair cells in its wake. Fibroblast growth factor signaling is involved in several aspects of the process--migration, deposition of a primordium, and differentiation.
- Developing the Lateral Line
A fish sensory organ develops when a wave of migrating primordial cells cyclically deposits rosettes of differentiated cells under the influence of fibroblast growth factor.Permalink: