08 July 2008
Vol 1, Issue 27

About The Cover

Cover image expansion

COVER This week's issue features a Review that discusses the metalloproteinase-independent functions of tissue inhibitors of metalloproteinases (TIMPs). The image shows how the binding of TIMP-2 (pink) to the α3β4 integrin inhibits receptor tyrosine kinase activity through the action of the protein tyrosine phosphatase Shp1. [Image: Chris Bickel, AAAS]