Signaling Networks and Mathematics

Sci. Signal., 28 October 2008
Vol. 1, Issue 43, p. eg7
DOI: 10.1126/scisignal.143eg7

Signaling Networks and Mathematics

  1. Michael B. Yaffe1,2,*
  1. 1Chief Scientific Editor of Science Signaling, American Association for the Advancement of Science, 1200 New York Avenue, N.W., Washington, DC 20005, USA.
  2. 2Koch Institute for Integrative Cancer Research, Departments of Biology and Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  1. *Corresponding author. E-mail: myaffe{at}


In order to fully appreciate and understand the complexity of cellular signaling, biologists are turning to mathematical models and computational approaches. Yaffe provides insight into his strategies for dividing and conquering papers that use complex math to make new predictions about biological systems.


M. B. Yaffe, Signaling Networks and Mathematics. Sci. Signal. 1, eg7 (2008).

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882