Focus Issue: An Expanding World for TGF-β Signaling

Sci. Signal., 18 November 2008
Vol. 1, Issue 46, p. eg8
DOI: 10.1126/scisignal.146eg8

Focus Issue: An Expanding World for TGF-β Signaling

  1. Nancy R. Gough*
  1. Editor of Science Signaling, American Association for the Advancement of Science, 1200 New York Avenue, N.W., Washington, DC 20005, USA.
  1. *Corresponding author. E-mail: ngough{at}


The complexity of the signaling network that is initiated by members of the transforming growth factor–β (TGF-β) superfamily continues to increase. In addition, Smads, which were originally identified as key transducers of TGF-β signals, are beginning to emerge as players in other TGF-β–independent processes. Perspectives in this issue, as well as highlights from a recent meeting on TGF-β and select resources from the Archives, spotlight this emerging complexity.


N. R. Gough, Focus Issue: An Expanding World for TGF-β Signaling. Sci. Signal. 1, eg8 (2008).

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