PerspectiveNeuroscience

An All-Purpose Tool for Axon Guidance

Science Signaling  25 Nov 2008:
Vol. 1, Issue 47, pp. pe50
DOI: 10.1126/scisignal.147pe50

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Abstract

The functions of the 75-kilodalton neurotrophin receptor p75NTR have remained enigmatic despite nearly three decades of study. Recent studies reveal that p75NTR is a versatile co-receptor that controls signaling by receptors for multiple ligands that provide repellant guidance cues to developing axons.

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