Editors' ChoiceCellular and Molecular Signaling

Papers of note in Science 354 (6319)

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Sci. Signal.  03 Jan 2017:
Vol. 10, Issue 460, eaam6503
DOI: 10.1126/scisignal.aam6503

This week’s articles highlight the development of hair and sweat glands in human skin, how calcium signals affect the sensitivity of a mouse’s whiskers, peptide hormone processing in plants, and conformational changes that enable bacteriorhodopsin to harvest energy from light.

DEVELOPMENT

How to grow hair or sweat glands

Mice and humans exploit the epithelial-mesenchymal circuitry in different ways to direct sweat gland or hair follicle generation.

NEUROSCIENCE

Now you feel it, now you don't

The threshold for perception is increased upon down-regulation of dendritic activity.

PLANT BIOLOGY

Prohormone processing by subtilases

Redundant proteases mediate the formation of a peptide signal for the abscission of floral organs in Arabidopsis.

STRUCTURAL BIOLOGY

Snapshots of bacteriorhodopsin

Time-resolved serial crystallography using an x-ray free electron laser reveals structural changes in bacteriorhodopsin.

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