Editors' ChoiceCellular and Molecular Signaling

Papers of note in Science 355 (6325)

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Sci. Signal.  14 Feb 2017:
Vol. 10, Issue 466,
DOI: 10.1126/scisignal.aam9556

This week’s articles report that neural activity promotes localized miRNA-mediated translational silencing at synapses and that activation of B cells triggers an unusual form of autophagy in these cells.

NEUROSCIENCE

Intraneuronal control of protein expression

Sambandan et al. report that local synaptic stimulation promotes localized maturation of a precursor microRNA and reduces target protein synthesis.

IMMUNOLOGY

Change for good

Martinez-Martin et al. found that an unusual form of autophagy is triggered after immunological B cell activation and tunes B cell responses to viral infection.

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