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Endoplasmic reticulum proteostasis in glioblastoma—From molecular mechanisms to therapeutic perspectives

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Sci. Signal.  14 Mar 2017:
Vol. 10, Issue 470, eaal2323
DOI: 10.1126/scisignal.aal2323

Article Information

vol. 10 no. 470

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History: 
  • Received October 18, 2016
  • Accepted December 21, 2016

Author Information

  1. Joanna Obacz1,2,*,
  2. Tony Avril1,2,*,
  3. Pierre-Jean Le Reste1,2,3,*,
  4. Hery Urra4,5,6,
  5. Véronique Quillien1,2,
  6. Claudio Hetz4,5,6,7,8, and
  7. Eric Chevet1,2,
  1. 1INSERM U1242, Chemistry, Oncogenesis, Stress Signaling, Université de Rennes 1, Rennes 35000, France.
  2. 2Centre de Lutte Contre le Cancer Eugène Marquis, Rennes 35042, France.
  3. 3Department of Neurosurgery, University Hospital Pontchaillou, Rennes 35000, France.
  4. 4Faculty of Medicine, Biomedical Neuroscience Institute, University of Chile, Santiago, Chile.
  5. 5Center for Geroscience, Brain Health and Metabolism, Santiago, Chile.
  6. 6Program of Cellular and Molecular Biology, Center for Molecular Studies of the Cell, Institute of Biomedical Sciences, University of Chile, 1027 Independencia, P.O. Box 70086, Santiago, Chile.
  7. 7Buck Institute for Research on Aging, Novato, CA 94945, USA.
  8. 8Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA 02115, USA.
  1. Corresponding author. Email: eric.chevet{at}inserm.fr
    • * These authors contributed equally to this work.

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