Editors' ChoiceCancer Immunology

Paper of note in Science 356 (6334)

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Sci. Signal.  18 Apr 2017:
Vol. 10, Issue 475, eaan4392
DOI: 10.1126/scisignal.aan4392

This week’s article highlights the contribution of T cell reactivity to nonviral antigens to the success of adoptive T cell transfer in treating a virus-driven cancer.

IMMUNOTHERAPY

Targeting nonviral antigens in viral-driven cancer

Stevanović et al. report that reactive T cells directed against nonviral antigens lead to regression of human papilloma virus–positive cervical cancer.

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