Vol 10, Issue 475
- The FOXM1 inhibitor RCM-1 suppresses goblet cell metaplasia and prevents IL-13 and STAT6 signaling in allergen-exposed mice
An inhibitor of the transcription factor FOXM1 prevents asthma-associated signaling in mice exposed to a common airborne allergen.
- Control of potassium homeostasis is an essential function of the second messenger cyclic di-AMP in Bacillus subtilis
The second messenger cyclic di-AMP enables bacteria to adapt to changes in environmental potassium concentrations.
This week’s article highlights the contribution of T cell reactivity to nonviral antigens to the success of adoptive T cell transfer in treating a virus-driven cancer.