Editors' ChoiceCellular and Molecular Signaling

Papers of note in Nature 544 (7650)

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Sci. Signal.  25 Apr 2017:
Vol. 10, Issue 476, eaan4393
DOI: 10.1126/scisignal.aan4393

This week’s articles show that vesicle fusion proteins are involved in long-term potentiation and highlight the structural properties that contribute to functional differences between angiotensin II receptors.

NEUROSCIENCE

Postsynaptic vesicle fusion for LTP

Wu et al. show that synaptotagmins are required postsynaptically for recruitment of AMPA receptors during NMDA receptor–dependent long-term potentiation.

BIOCHEMISTRY

Understanding an enigmatic receptor

Zhang et al. report structural features that contribute to the unusual signaling properties of the angiotensin II type 2 receptor (see also Tate).

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