Editors' ChoiceCellular and Molecular Signaling

Papers of note in Science 356 (6338)

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Sci. Signal.  16 May 2017:
Vol. 10, Issue 479, eaan6391
DOI: 10.1126/scisignal.aan6391

This week’s articles demonstrate how T cells search for ligands; a role for the endoplasmic reticulum in the nonclathrin-mediated endocytosis of a growth factor receptor; and growth coupling between distant bacterial colonies that enables the cells to share limited resources.

IMMUNOLOGY

Search and capture in space and time

Cai et al. showed that T cells of the immune system palpate opposing cell surfaces in their search for ligands.

CELL BIOLOGY

ER-PM contacts in nonclathrin endocytosis

Caldieri et al. dissected an alternate mechanism for epidermal growth factor receptor endocytosis (see also Tan and Anderson).

SYSTEMS BIOLOGY

Maximizing growth by sharing

Liu et al. demonstrate how sharing resources can benefit bacterial colonies (see also Gordon).

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