Editors' ChoiceCellular and Molecular Signaling

Papers of note in Science 356 (6340)

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Sci. Signal.  30 May 2017:
Vol. 10, Issue 481, eaan8309
DOI: 10.1126/scisignal.aan8309

This week’s articles highlight new research that identifies a microRNA decay pathway that promotes cell cycle progression; an interactive atlas of the subcellular localization of thousands of human proteins, which may help refine signaling networks; and a review of symbiotic plant-microbe interactions.

CELL BIOLOGY

Breaking down miRNAs

Elbarbary et al. identify an endonuclease that initiates decay of microRNAs that regulate the cell cycle.

PROTEOMICS

Mapping the proteome

Thul et al. generated the Cell Atlas, an image-based collection of 12,003 proteins and 13 organelles that reveals proteins that exhibit multiple localizations and single-cell variation (see also Horwitz and Johnson).

HOST-MICROBE INTERACTIONS

Taking a look at plant-microbe relationships

Martin et al. review the evolution of plant-symbiont interactions that modulate plant signaling pathways, development, and immunity.

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