Research ArticleMetabolism

TRIF-dependent Toll-like receptor signaling suppresses Scd1 transcription in hepatocytes and prevents diet-induced hepatic steatosis

See allHide authors and affiliations

Sci. Signal.  08 Aug 2017:
Vol. 10, Issue 491, eaal3336
DOI: 10.1126/scisignal.aal3336

Article Information

vol. 10 no. 491

PubMed: 
Published By: 
Print ISSN: 
Online ISSN: 
History: 
  • Received November 4, 2016
  • Resubmitted April 13, 2017
  • Accepted July 21, 2017

Author Information

  1. Jing Chen1,2,*,
  2. Jin Li1,3,4,*,
  3. Jensen H. C. Yiu1,2,
  4. Jenny K. W. Lam2,
  5. Chi-Ming Wong1,3,
  6. Bernhard Dorweiler5,
  7. Aimin Xu1,2,3,, and
  8. Connie W. Woo1,2,
  1. 1State Key Laboratory of Pharmaceutical Biotechnology, University of Hong Kong, Hong Kong 999077, China.
  2. 2Department of Pharmacology and Pharmacy, University of Hong Kong, Hong Kong 999077, China.
  3. 3Department of Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong 999077, China.
  4. 4Department of Endocrinology, Second Hospital of Shanxi Medical University, Taiyuan 030001, China.
  5. 5Division of Vascular Surgery, Department of Cardiothoracic and Vascular Surgery, University Medical Center Mainz, Mainz 55131, Germany.
  1. Corresponding author. Email: cwhwoo{at}hku.hk (C.W.W.); amxu{at}hku.hk (A.X.)
    • * These authors contributed equally to this work.

    Altmetric

    Article usage

    Article usage: August 2017 to May 2018

    AbstractFullPdf
    Aug 20173978128226
    Sep 20171954739
    Oct 20171332134
    Nov 2017862616
    Dec 2017871210
    Jan 2018851721
    Feb 20188196
    Mar 20181552423
    Apr 2018125228
    May 20187678