Editors' ChoiceMEDICINE

Paper of note in Science Translational Medicine 9 (406)

See allHide authors and affiliations

Sci. Signal.  12 Sep 2017:
Vol. 10, Issue 496, eaap9099
DOI: 10.1126/scisignal.aap9099

This week’s article describes how targeted antimicrobials may reduce the virulence of Clostridium difficile infection.

MICROBIOLOGY

Forcing microbes to make a diff-icult decision

Kirk et al. uncovered important roles for S-layer protein A (SlpA) in Clostridium difficile for the bacteria’s sporulation, resistance to innate immunity effectors, and toxin production.

Highlighted Article

View Abstract

Navigate This Article