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Papers of note in Science Translational Medicine 9 (410)

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Sci. Signal.  10 Oct 2017:
Vol. 10, Issue 500, eaaq0801
DOI: 10.1126/scisignal.aaq0801

This week’s article and a review describe ways to potentially improve immunotherapy for cancer patients.

CANCER IMMUNOTHERAPY

Double trouble for solid tumors

Ishiguro et al. report a bispecific T cell–redirecting antibody that directs T cells to tumor cells by engaging CD3 on T cells and glypican-3 on tumor cells.

In a Review, Pinter and Jain discuss how targeting the renin-angiotensin system might improve cancer immunotherapy.

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