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Papers of note in Science Translational Medicine 9 (411)

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Sci. Signal.  17 Oct 2017:
Vol. 10, Issue 501, eaar2006
DOI: 10.1126/scisignal.aar2006

This week’s articles describe ways to potentially prevent heart failure after myocardial infarction and treat the autoimmune disease plaque psoriasis.

CARDIOVASCULAR DISEASE

Lipoprotein lends a hand for heart attacks

Heywood et al. report that in both healthy and insulin-resistant mice, administration of high-density lipoprotein after a heart attack increases cardiac glucose uptake and function through activation of AKT signaling.

AUTOIMMUNE DISEASE

Nixing IL-36 in psoriasis

Mahil et al. show that the cytokine IL-36 mediates the inflammation associated with plaque psoriasis.

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