Research ArticleFRAGILE X SYNDROME

Aberrant Rac1-cofilin signaling mediates defects in dendritic spines, synaptic function, and sensory perception in fragile X syndrome

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Sci. Signal.  07 Nov 2017:
Vol. 10, Issue 504, eaan0852
DOI: 10.1126/scisignal.aan0852

Article Information

vol. 10 no. 504

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History: 
  • Received March 3, 2017
  • Accepted September 29, 2017

Author Information

  1. Alexander Pyronneau1,
  2. Qionger He2,
  3. Jee-Yeon Hwang1,
  4. Morgan Porch1,
  5. Anis Contractor2,3, and
  6. R. Suzanne Zukin1,*
  1. 1Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, New York, NY 10461, USA.
  2. 2Department of Physiology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
  3. 3Department of Neurobiology, Weinberg College of Arts and Sciences, Northwestern University, Evanston, IL 60208, USA.
  1. *Corresponding author. Email: suzanne.zukin{at}einstein.yu.edu

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