Research ArticleFRAGILE X SYNDROME

Neuronal activity drives FMRP- and HSPG-dependent matrix metalloproteinase function required for rapid synaptogenesis

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Sci. Signal.  07 Nov 2017:
Vol. 10, Issue 504, eaan3181
DOI: 10.1126/scisignal.aan3181

Article Information

vol. 10 no. 504

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History: 
  • Received March 30, 2017
  • Accepted October 13, 2017

Author Information

  1. Mary L. Dear1,*,
  2. Jarrod Shilts1,, and
  3. Kendal Broadie1,2,3,*,
  1. 1Department of Biological Sciences, Vanderbilt University, Nashville, TN 37232, USA.
  2. 2Department of Cell and Developmental Biology, Vanderbilt University and Medical School, Nashville, TN 37232, USA.
  3. 3Vanderbilt Brain Institute, Vanderbilt University and Medical School, Nashville, TN 37232, USA.
  1. Corresponding author. Email: kendal.broadie{at}vanderbilt.edu
  • * Present address: 6270A Medical Research Building III, Vanderbilt University, 465 21st Avenue South, Nashville, TN 37232, USA.

  • Present address: Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK.

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