Editors' ChoiceCancer Immunotherapy

CAFs complicate immunotherapy

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Sci. Signal.  28 Nov 2017:
Vol. 10, Issue 507, eaar5583
DOI: 10.1126/scisignal.aar5583

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Anti-CSF1R immunotherapy effectively inhibits one suppressive immune cell type but unleashes another through cancer-associated fibroblasts.

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