Research ArticleCancer Metabolism

The receptor tyrosine kinase EphA2 promotes glutamine metabolism in tumors by activating the transcriptional coactivators YAP and TAZ

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Sci. Signal.  05 Dec 2017:
Vol. 10, Issue 508, eaan4667
DOI: 10.1126/scisignal.aan4667

Article Information

vol. 10 no. 508

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History: 
  • Received April 17, 2017
  • Accepted November 2, 2017

Author Information

  1. Deanna N. Edwards1,
  2. Verra M. Ngwa2,
  3. Shan Wang1,
  4. Eileen Shiuan2,3,
  5. Dana M. Brantley-Sieders1,
  6. Laura C. Kim2,
  7. Albert B. Reynolds2, and
  8. Jin Chen1,2,4,5,6,*
  1. 1Division of Rheumatology and Immunology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
  2. 2Department of Cancer Biology, Vanderbilt University, Nashville, TN 37232, USA.
  3. 3Medical Scientist Training Program, Vanderbilt University, Nashville, TN 37232, USA.
  4. 4Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN 37232, USA.
  5. 5Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
  6. 6Veterans Affairs Medical Center, Tennessee Valley Healthcare System, Nashville, TN 37212, USA.
  1. *Corresponding author. Email: jin.chen{at}vanderbilt.edu

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