Research ArticleCell death

Ca2+-dependent demethylation of phosphatase PP2Ac promotes glucose deprivation–induced cell death independently of inhibiting glycolysis

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Sci. Signal.  09 Jan 2018:
Vol. 11, Issue 512, eaam7893
DOI: 10.1126/scisignal.aam7893

Article Information

vol. 11 no. 512

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History: 
  • Received January 19, 2017
  • Resubmitted October 16, 2017
  • Accepted December 14, 2017

Author Information

  1. Ha Yin Lee1,
  2. Yoko Itahana1,
  3. Stefan Schuechner2,
  4. Masahiro Fukuda3,
  5. H. Shawn Je3,
  6. Egon Ogris2,
  7. David M. Virshup1,4,5, and
  8. Koji Itahana1,*
  1. 1Programme in Cancer and Stem Cell Biology, Duke-NUS Medical School, 8 College Road, 169857, Singapore.
  2. 2Department of Medical Biochemistry, Max F. Perutz Laboratories, Medical University of Vienna, Dr. Bohr-Gasse 9, 1030 Vienna, Austria.
  3. 3Programme in Neuroscience and Behavioural Disorders, Duke-NUS Medical School, 8 College Road, 169857, Singapore.
  4. 4Department of Biochemistry, National University of Singapore, 8 Medical Drive, 117596, Singapore.
  5. 5Department of Pediatrics, Duke University School of Medicine, Durham, NC 27710, USA.
  1. *Corresponding author. Email: koji.itahana{at}duke-nus.edu.sg

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