Editors' ChoiceCancer

Epigenetic ignition of melanoma

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Sci. Signal.  13 Mar 2018:
Vol. 11, Issue 521, eaat5334
DOI: 10.1126/scisignal.aat5334

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The histone demethylases LSD1 and JMJD2C enable premalignant melanocytes to escape oncogene-induced senescence and form aggressive melanomas.

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