Research ArticleDRUG DEVELOPMENT The nuclear translocation of the kinases p38 and JNK promotes inflammation-induced cancer Galia Maik-Rachline1, Elder Zehorai1, Tamar Hanoch1, John Blenis2, and Rony Seger1,*1Department of Biological Regulation, The Weizmann Institute of Science, Rehovot 76100, Israel.2Weill Cornell Medicine, New York, NY 10021, USA.↵*Corresponding author. Email: rony.seger{at}weizmann.ac.il See allHide authors and affiliations Sci. Signal. 10 Apr 2018:Vol. 11, Issue 525, eaao3428DOI: 10.1126/scisignal.aao3428 Galia Maik-RachlineDepartment of Biological Regulation, The Weizmann Institute of Science, Rehovot 76100, Israel.Find this author on Google Scholar Find this author on PubMed Search for this author on this site ORCID record for Galia Maik-Rachline Elder ZehoraiDepartment of Biological Regulation, The Weizmann Institute of Science, Rehovot 76100, Israel.Find this author on Google Scholar Find this author on PubMed Search for this author on this site ORCID record for Elder Zehorai Tamar HanochDepartment of Biological Regulation, The Weizmann Institute of Science, Rehovot 76100, Israel.Find this author on Google Scholar Find this author on PubMed Search for this author on this site John BlenisWeill Cornell Medicine, New York, NY 10021, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site ORCID record for John Blenis Rony SegerDepartment of Biological Regulation, The Weizmann Institute of Science, Rehovot 76100, Israel.Find this author on Google Scholar Find this author on PubMed Search for this author on this site ORCID record for Rony Seger For correspondence: rony.seger@weizmann.ac.il Article Figures & Data Info & Metrics eLetters PDF Article Information vol. 11 no. 525 DOI: https://doi.org/10.1126/scisignal.aao3428 PubMed: 29636389 Published By: Science Signaling Print ISSN: 1945-0877 Online ISSN: 1937-9145 History: Received July 10, 2017Accepted March 22, 2018 Copyright & Usage: Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works http://www.sciencemag.org/about/science-licenses-journal-article-reuseThis is an article distributed under the terms of the Science Journals Default License. Author Information Galia Maik-Rachline1, Elder Zehorai1, Tamar Hanoch1, John Blenis2, and Rony Seger1,*1Department of Biological Regulation, The Weizmann Institute of Science, Rehovot 76100, Israel.2Weill Cornell Medicine, New York, NY 10021, USA.↵*Corresponding author. Email: rony.seger{at}weizmann.ac.il Altmetric Article usage Article lifetimeLast 6 monthsThis monthArticle usage: April 2018 to April 2018 AbstractFullPdf Apr 2018364513651250 View Full Text
The nuclear translocation of the kinases p38 and JNK promotes inflammation-induced cancer By Galia Maik-Rachline, Elder Zehorai, Tamar Hanoch, John Blenis, Rony Seger Sci. Signal.10 Apr 2018 A p38/JNK nuclear translocation–blocking peptide may be therapeutic in various cancers and inflammation-associated diseases.
The nuclear translocation of the kinases p38 and JNK promotes inflammation-induced cancer By Galia Maik-Rachline, Elder Zehorai, Tamar Hanoch, John Blenis, Rony Seger Sci. Signal.10 Apr 2018 A p38/JNK nuclear translocation–blocking peptide may be therapeutic in various cancers and inflammation-associated diseases.