Meeting Report

MEETING REPORT: Signaling Themes Shared Between Peptide and Steroid Hormones at the Plasma Membrane

Science's STKE  14 Dec 1999:
Vol. 1999, Issue 12, pp. pe1
DOI: 10.1126/stke.1999.12.pe1

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A review of the meeting "Steroid Receptor Family Members in the Plasma Membrane: The Proteins and their Functions," FASEB Summer Research Conference, Copper Mountain, Colorado, 8 through 13 August 1999


Steroid hormone receptors are primarily thought of as transcriptional regulators that are activated by ligand binding. However, there is also evidence for "nongenomic" actions of steroid hormones. Cheryl Watson summarizes a recent meeting that brought together researchers exploring these rapid effects of steroid hormones that occur in the absence of new protein synthesis. Current evidence for the existence of membrane steroid receptors, which may or may not be related to the well-known nuclear receptors, is discussed.

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