Computational Implications of Cooperative Plasticity Induction at Nearby Dendritic Sites

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Science Signaling  06 Jan 2009:
Vol. 2, Issue 52, pp. pe2
DOI: 10.1126/scisignal.151pe55

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Recent studies have revealed that plasticity is not regulated independently at individual synapses but rather that there is cooperativity or associativity between nearby synapses in the dendritic tree of individual cortical pyramidal cells. Here, I summarize experimental results regarding such cooperative plasticity and its underlying mechanisms and consider their computational implications.

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