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COVER This week's issue features a Meeting Report on a conference that was held in Hamburg, Germany, from 14 to 17 September 2008, on signaling mechanisms mediated by nicotinamide adenine dinucleotide (NAD+) and its metabolites. [Image: Kevin Forest, Getty Images]

Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882