31 March 2009
Vol 2, Issue 64

About The Cover

Cover image expansion

COVER This week's issue features a Perspective that discusses the shedding of the extracellular portion (ectodomain) of syndecan transmembrane proteoglycans. The image shows that shed syndecan ectodomains sequester the ligands for growth factor and chemokine receptors, thereby inhibiting signaling through these receptors. [Image: Preston Huey, AAAS]