Plant biology

ABA Receptor Rumbled?

Science Signaling  26 May 2009:
Vol. 2, Issue 72, pp. ec177
DOI: 10.1126/scisignal.272ec177

The plant hormone abscisic acid (ABA) is critical for normal development and for mediating plant responses to stressful environmental conditions. Now, two papers present analyses of candidate ABA receptors. Ma et al. and Park et al. used independent strategies to search for proteins that physically interact with ABI family phosphatase components of the ABA response signaling pathway. Both groups identified different members of the same family of proteins, which appear to interact with ABI proteins to form a heterocomplex that can act as the ABA receptor. The variety of both families suggests that the ABA receptor may not be one entity but rather a class of closely related complexes, which may explain previous difficulties in establishing its identity.

S.‐Y. Park, P. Fung, N. Nishimura, D. R. Jensen, H. Fujii, Y. Zhao, S. Lumba, J. Santiago, A. Rodrigues, T.‐f. F. Chow, S. E. Alfred, D. Bonetta, R. Finkelstein, N. J. Provart, D. Desveaux, P. L. Rodriguez, P. McCourt, J.‐K. Zhu, J. I. Schroeder, B. F. Volkman, S. R. Cutler, Abscisic acid inhibits type 2C protein phosphatases via the PYR/PYL family of START proteins. Science 324, 1068–1071 (2009). [Abstract] [Full Text]

Y. Ma, I. Szostkiewicz, A. Korte, D. Moes, Y. Yang, A. Christmann, E. Grill, Regulators of PP2C phosphatase activity function as abscisic acid sensors. Science 324, 1064–1068 (2009). [Abstract] [Full Text]