Editorial GuideNeuroscience

Focus Issue: Signals to Neurodegeneration

Science Signaling  21 Jul 2009:
Vol. 2, Issue 80, pp. eg9
DOI: 10.1126/scisignal.280eg9

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Abstract

Neurodegenerative diseases exact a tremendous toll on afflicted individuals and their families. Understanding the underlying signaling cascades that are perturbed by or contribute to neurodegeneration may identify new therapeutic targets or improve current therapies. The pieces in this Focus Issue of Science Signaling discuss molecular mechanisms and signaling pathways implicated in the pathologies of Parkinson's, Alzheimer's, and Huntington's diseases.

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