Vol 2, Issue 88
- Tks5-Dependent, Nox-Mediated Generation of Reactive Oxygen Species Is Necessary for Invadopodia Formation
Localized production of reactive oxygen species is key for cellular invasiveness and may be involved in a positive feedback loop with proteins that organize their site of production.
- Differential Interactions of FGFs with Heparan Sulfate Control Gradient Formation and Branching Morphogenesis
Manipulation of the interaction of a morphogen with the extracellular matrix changes its biological activities by altering its diffusion.
Tks proteins organize NADPH oxidase activity and localized production of reactive oxygen species in invasive cells.