Cyclic ADP Ribose as a Calcium-Mobilizing Messenger

See allHide authors and affiliations

Science's STKE  18 Jul 2000:
Vol. 2000, Issue 41, pp. pe1
DOI: 10.1126/stke.2000.41.pe1

You are currently viewing the abstract.

View Full Text


This Perspective by Galione and Churchill is one in a series on intracellular calcium release mechanisms. The authors review the evidence for cyclic adenosine diphosphate ribose (cADPR) being a second messenger involved in regulating intracellular calcium. In addition, the physiological stimuli and responses mediated by cADPR are discussed. The Perspective is accompanied by a movie showing a calcium wave triggered by cADPR.

View Full Text