MAP Kinases and the Regulation of Nuclear Receptors

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Science's STKE  05 Sep 2000:
Vol. 2000, Issue 48, pp. pe1
DOI: 10.1126/stke.2000.48.pe1

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The activity of nuclear receptors or ligand-activated transcription factors can be regulated both positively and negatively by signals transduced through mitogen-activated protein kinase (MAPK) signaling cascades. Kyriakis discusses how cross talk between MAPK signaling and nuclear receptor signaling occurs and the effect this cross talk has on nuclear receptor function.

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