Coregulation of Ion Channels by Neurosteroids and Phosphorylation

Science's STKE  21 Nov 2000:
Vol. 2000, Issue 59, pp. pe1
DOI: 10.1126/stke.2000.59.pe1

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This Perspective by Tasker is one of two discussing the regulation of ion channels by neurosteroids. Neurosteroids are steroids synthesized in the brain that act as allosteric modulators of ion-channel activity. The dual regulation of γ-aminobutyric acid type A (GABAA) receptors and voltage-gated calcium channels by phosphorylation and neurosteroids is the focus of this Perspective.

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