Editors' ChoiceMolecular Physiology

Cardiac Function

Science's STKE  15 Jan 2002:
Vol. 2002, Issue 115, pp. tw23
DOI: 10.1126/stke.2002.115.tw23

This week's issue of Nature contains a large section devoted to cardiology. Of those articles, several are of a molecular nature, and may be of interest to STKE readers. Bers reviews the mechanisms that govern the transport of ions across membranes leading to the highly orchestrated contraction of the heart, whereas Marbán reviews how mutations and chronic modifications of various ion channels can lead to cardiac arrhythmias and heart failure. Rockman et al. review the G protein-coupled receptors known to be involved in cardiac function.

D. M. Bers, Cardiac excitation-contraction coupling. Nature 415, 198-205 (2002). [Online Journal]

E. Marbán, Cardiac channelopathies. Nature 415, 213-218 (2002). [Online Journal]

H. A. Rockman, W. J. Koch, R. J. Lefkowitz, Seven-transmembrane-spanning receptors and heart function. Nature 415, 206-212 (2002). [Online Journal]