Argosomes: Intracellular Transport Vehicles for Intercellular Signals?

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Science's STKE  19 Mar 2002:
Vol. 2002, Issue 124, pp. pe13
DOI: 10.1126/stke.2002.124.pe13

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Cell clusters in the immature tissues of developing organisms create morphogen gradients that guide cellular differentiation into specific cell fates. Although the process of simple diffusion in gradient establishment has been well studied, there are other mechanisms by which cells establish morphogen gradients. Christian discusses the recent findings that morphogens may establish gradients through the use of plasma membrane-containing exovesicles, termed "argosomes."

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