Opening Pandora's Box: Clinical Data and the Study of Complex Diseases

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Science's STKE  30 Apr 2002:
Vol. 2002, Issue 130, pp. pe20
DOI: 10.1126/stke.2002.130.pe20

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Complex diseases have complex phenotypes, and proper diagnosis requires that the analysis take into account the patient's history and exposure to environmental factors, as well as genetic information. Signaling information is one aspect of a grander "biomedical informatics" approach advocated for a better understanding of a patient's medically relevant disease phenotype.

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