Editors' ChoicePeroxisomes

Making the Most of the Light

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Science's STKE  23 Jul 2002:
Vol. 2002, Issue 142, pp. tw267-TW267
DOI: 10.1126/stke.2002.142.tw267

Peroxisomes are small intracellular organelles involved in metabolism. In mammals, abnormal peroxisomes can cause effects ranging from skin disorders to neuropathologies. Studies in the plant Arabidopsis by Hu et al. now show that peroxisomes are critical for normal photomorphogenesis. The plant peroxisomal protein AtPex2p is required for normal growth. Mutations in its gene suppress growth defects caused by mutations in Det, which encodes a nuclear protein that regulates expression of photomorphogenesis genes.

J. Hu, M. Aguirre, C. Peto, J. Alonso, J. Ecker, J. Chory, A role for peroxisomes in photomorphogenesis and development of Arabidopsis, Science 297, 405-409 (2002). [Abstract] [Full Text]

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