Plant biology

Plant Pathogen Target

Science's STKE  02 Sep 2003:
Vol. 2003, Issue 198, pp. tw341-TW341
DOI: 10.1126/stke.2003.198.tw341

Many pathogens of mammals and plants use a conserved delivery system, the type III secretion system, to inject virulence factors into their hosts. However, few of the host targets are known, and how the plant surveillance system works is not well understood. Shao et al. show in Arabidopsis that a protein kinase, PBS1, is the host target for a Pseudomonas syringae virulence protein, AvrPphB, a cysteine protease that cleaves PBS1. The resulting fragment of PBS1 autophosphorylates and, possibly in conjunction with AvrPphB, is then recognized by the plant resistance protein RPS5.

F. Shao, C. Golstein, J. Ade, M. Stoutemyer, J. E. Dixon, R. W. Innes, Cleavage of Arabidopsis PBS1 by a bacterial type III effector. Science 301, 1230-1233 (2003). [Abstract] [Full Text]