Plant biology

Getting from the Tip to the Root

Science's STKE  02 Nov 2004:
Vol. 2004, Issue 257, pp. tw400
DOI: 10.1126/stke.2572004tw400

Auxin hormone signaling normally runs from the tip of a plant to its root and directs a wide variety of developmental events along the way. The polarity of auxin transport is established by the asymmetric localization of the auxin efflux carrier PIN. What causes PIN to be localized to one end of the cell and not the other is now elucidated by Friml et al. (see the Perspective by Kaplinsky and Barton). The PINOID kinase controls localization of the PIN auxin efflux carrier, placing it at one end of the cell or the other, controlling the direction of auxin flow.

J. Friml, X. Yang, M. Michniewicz, D. Weijers, A. Quint, O. Tietz, R. Benjamins, P. B. F. Ouwerkerk, K. Ljung, G. Sandberg, P. J. J. Hooykaas, K. Palme, R. Offringa, A PINOID-dependent binary switch in apical-basal PIN polar targeting directs auxin efflux. Science 306, 862-865 (2004). [Abstract] [Full Text]

N. J. Kaplinsky, M. K. Barton, Plant acupuncture: Sticking PINs in the right places. Science 306, 822-823 (2004). [Summary] [Full Text]