Teaching Resource

Calcium-Triggered Exocytosis and Clathrin-Mediated Endocytosis of Synaptic Vesicles

Science's STKE  18 Jan 2005:
Vol. 2005, Issue 267, pp. tr1
DOI: 10.1126/stke.2672005tr1


The animation illustrates the recruitment, calcium-triggered exocytosis, and clathrin-mediated endocytosis of synaptic vesicles. The animation shows not only the proteins involved in synaptic vesicle fusion and recycling, but also changes in the lipid composition that are important for targeting of proteins to sites of membrane internalization. The animation would be useful in both neurobiology courses, but also any cell biology course that explores clathrin-mediated endocytic and calcium-regulated secretion events.