Plant biology

Brassinosteroid Signaling Pathway

Science's STKE  15 Mar 2005:
Vol. 2005, Issue 275, pp. tw104
DOI: 10.1126/stke.2752005tw104

Plants lacking a type of steroid--brassinosteroid--are likely to be dwarfed, to have curled leaves, and to exhibit an ineffective growth pattern in the dark. Brassinosteroids bind to receptors at the plant cell surface and initiate a signaling cascade that involves nuclear factors, including BZR1 and BZR2. He et al. (see the Perspective by Sablowski and Harberd) have now characterized aspects of the signaling pathway for brassinosteroids in detail and find that BZR1 is a DNA binding protein that functions as a transcriptional repressor.

J.-X. He, J. M. Gendron, Y. Sun, S. S. L. Gampala, N. Gendron, C. Q. Sun, Z.-Y. Wang, BZR1 is a transcriptional repressor with dual roles in brassinosteroid homeostasis and growth responses. Science 307, 1634-1638 (2005). [Abstract] [Full Text]

R. Sablowski, N. P. Harberd, Plant genes on steroids. Science 307, 1569-1570 (2005). [Summary] [Full Text]