Teaching Resource

Structure of G Protein–Coupled Receptors and G Proteins

Science's STKE  22 Mar 2005:
Vol. 2005, Issue 276, pp. tr10
DOI: 10.1126/stke.2762005tr10

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This Teaching Resource provides lecture notes and slides for a class covering the structure and function of G protein–coupled receptors and is part of the course "Cell Signaling Systems: A Course for Graduate Students." The lecture begins with a discussion of the crystal structure of rhodopsin and G protein subunits and then proceeds to describe the molecular mechanisms of receptor activation and the subsequent release of G proteins.

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