Perspective

Food Fight: The NPY-Serotonin Link Between Aggression and Feeding Behavior

Science's STKE  29 Mar 2005:
Vol. 2005, Issue 277, pp. pe12
DOI: 10.1126/stke.2772005pe12

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Abstract

Aggressive behavior in mammals is linked to feeding. Interactions between neuropeptide tyrosine (NPY) and serotonergic neurons provide this link. Studies of aggressive behavior in mice in which the Y1 subtype of NPY receptor was knocked out further define the synaptic circuits responsible for the interrelation of these instinctive behaviors.

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