Teaching Resource

G Protein–Coupled Receptors

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Science's STKE  12 Apr 2005:
Vol. 2005, Issue 279, pp. tr11
DOI: 10.1126/stke.2792005tr11

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This Teaching Resource provides lecture notes and slides for a class covering G protein–coupled receptors (GPCRs) and is part of the course "Cell Signaling Systems: A Course for Graduate Students." The lecture begins with a discussion of the major classes of GPCRs and then proceeds to describe the mechanisms of receptor diversity, ligand interaction, desensitization, coupling, and mutations associated with human diseases.

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