Teaching Resource

Regulation of Complexes by Cytoskeletal Elements: Integrins Serve as Force Transducers Linking Mechanical Stimuli and Biochemical Signals

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Science's STKE  06 Dec 2005:
Vol. 2005, Issue 313, pp. tr27
DOI: 10.1126/stke.3132005tr27

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Abstract

This Teaching Resource provides a summary and slides derived from a lecture on the integrin family members and the downstream signaling pathways they activate; it is part of the course "Cell Signaling Systems: A Course for Graduate Students." The lecture focuses on the capacity of integrins to serve as mechanotransducers, with particular emphasis on signaling mechanisms downstream of integrins.

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