Editors' ChoicePlant biology

Providing Direction for Auxin Trafficking

See allHide authors and affiliations

Science's STKE  30 May 2006:
Vol. 2006, Issue 337, pp. tw185
DOI: 10.1126/stke.3372006tw185

The "where" of auxin signaling is critical to regulating developmental responses during plant growth. Auxin is shunted through cells from one place to the next using influx and efflux carriers. The localization of these carriers thus has a direct effect on auxin signaling. Dharmasiri et al. have now cloned the AXR4 gene and show that the auxin influx carrier is localized according to directions provided by the AXR4 protein.

S. Dharmasiri, R. Swarup, K. Mockaitis, N. Dharmasiri, S. K. Singh, M. Kowalchyk, A. Marchant, S. Mills, G. Sandberg, M. J. Bennett, M. Estelle, AXR4 is required for localization of the auxin influx facilitator AUX1. Science 312, 1218-1220 (2006). [Abstract] [Full Text]